Generic name:promethazine (rectal route) [ proe-METH-a-zeen ]
Drug classes:Antihistamines, Phenothiazine antiemetics
Medically reviewed by Drugs.com. Last updated on May 7, 2022.
Promethazine hydrochloride should not be used in pediatric patients less than 2 years of age because of the potential for fatal respiratory depression. Postmarketing cases of respiratory depression, including fatalities, have been reported with use of promethazine hydrochloride in pediatric patients less than 2 years of age. A wide range of weight-based doses of promethazine hydrochloride have resulted in respiratory depression in these patients. Caution should be exercised when administering promethazine hydrochloride to pediatric patients 2 years or age and older. It is recommended that the lowest effective dose of promethazine hydrochloride be used in pediatric patients 2 years of age and older and concomitant administration of other drugs with respiratory depressant effects be avoided .
Commonly used brand name(s)
In the U.S.
- Phenadoz
- Phenergan
- Promethegan
Available Dosage Forms:
- Suppository
Therapeutic Class: Gastrointestinal Agent
Pharmacologic Class: Antihistamine
Chemical Class: Aliphatic
Uses for Phenergan
Promethazine is used to relieve or prevent the symptoms of hay fever, allergic conjunctivitis (inflammation of the eye), and other types of allergy or allergic reactions. It works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. It can sometimes close up the bronchial tubes (air passages of the lungs) and make breathing difficult .
Promethazine is also used to prevent and control motion sickness, nausea, vomiting, and dizziness. In addition, it may be used to help people go to sleep and control their pain or anxiety before or after surgery or other procedures .
Promethazine may also be used for o..
