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Phentermine and topiramate
  • Treatments
  • Obesity

Phentermine and topiramate

Generic name: phentermine and topiramate [ FEN-ter-meen-and-toe-PIR-a-mate ]
Brand name: Qsymia
Dosage form: oral capsule, extended release (11.25 mg-69 mg; 15 mg-92 mg; 3.75 mg-23 mg; 7.5 mg-46 mg)
Drug class:Anorexiants

Medically reviewed by Drugs.com on Nov 24, 2020. Written by Cerner Multum.

What is phentermine and topiramate?

Phentermine and topiramate is a combination medicine used together with diet and exercise to treat obesity.

phentermine and topiramate is sometimes used to treat obesity that may be related to diabetes, high cholesterol, or high blood pressure. Phentermine and topiramate will not treat these underlying conditions. Keep using any other medicines your doctor has prescribed.

Phentermine and topiramate may also be used for purposes not listed in this medication guide.

Warnings

Do not use if you are pregnant or if you become pregnant. This medicine may increase the risk of a birth defect called cleft lip and palate in a newborn.

Phentermine and topiramate can increase your resting heart rate. Tell your doctor if you have fast or pounding heartbeats while you are resting.

Topiramate may cause vision problems that can be permanent if not treated quickly. Call your doctor right away if you have a sudden decrease in vision.

Some people have thoughts about suicide while taking topiramate. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

Before taking this medicine

Do not use phentermine and topiramate if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You should not use this medicine if you are allergic to phentermine or topiramate, or if you have:

  • glaucoma;

  • overactive thyroid; or

  • if you are pregnant or may become pregnant.

You may need to have a negative pregnancy test before starting this treatment. Do not use phentermine and topiramate if you are pregnant. Stop taking this medicine and call your doc...