Pirfenidone Tablets
Dosage form: tablet, film coated
Drug class:Miscellaneous uncategorized agents
Medically reviewed by Drugs.com. Last updated on Jun 1, 2022.
On This Page
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Drug Interactions
- Use In Specific Populations
- Overdosage
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- Clinical Studies
- How Supplied/Storage and Handling
- Patient Counseling Information
Indications and Usage for Pirfenidone Tablets
Pirfenidone Tablets are indicated for the treatment of idiopathic pulmonary fibrosis (IPF).
Pirfenidone Tablets Dosage and Administration
Testing Prior to Pirfenidone Tablets Administration
Conduct liver function tests prior to initiating treatment with Pirfenidone Tablets [see Warnings and Precautions (5.1)].
Recommended Dosage
Upon initiation of treatment, titrate to the full dosage of 2403 mg/day over a 14-day period as follows:
| Treatment days | Dosage |
|---|---|
| Days 1 through 7 | 267 mg three times daily (801 mg/day) |
| Days 8 through 14 | 534 mg three times daily (1602 mg/day) |
| Days 15 onward | 801 mg three times daily (2403 mg/day) |
Dosages above 2403 mg/day are not recommended for any patient. Patients should not take 2 doses at the same time to make up for a missed dose. Patients should not take more than 3 doses per day.
Dosage Modifications due to Adverse Reactions
Patients who miss 14 or more days of pirfenidone should re-ini...
