Plenaxis

Generic name: abarelix [ a-BAR-eh-lix ]
Drug classes:Gonadotropin-releasing hormone antagonists, Hormones / antineoplastics

Medically reviewed by Drugs.com. Last updated on Feb 3, 2022.

What is Plenaxis?

Plenaxis reduces the amount of testosterone produced in the body.

Plenaxis is used in the palliative treatment of advanced prostate cancer.

Plenaxis may also be used for purposes other than those listed in this medication guide.

Warnings

In some cases, the use of Plenaxis has resulted in serious allergic reactions. An allergic reaction may occur after any injection of the medication, including, but not limited to the first dose. Patients should be observed in the doctor's office for at least 30 minutes following each dose so that immediate treatment of an allergic reaction can be obtained if needed.

Treatment with Plenaxis may become less effective over time in some patients. Monitoring blood levels of testosterone will be done on a regular basis with blood tests to monitor the effectiveness of the medication.

Plenaxis is not intended for use by women. Plenaxis is in the FDA pregnancy category X. This means that Plenaxis will cause birth defects in an unborn baby. Do not use this medication if you are pregnant or if you could become pregnant during treatment.

Before using Plenaxis

Before using Plenaxis, tell your doctor if you

• have irregular heartbeats;

• have liver problems;

• have osteoporosis; or

• weigh more than 225 pounds.

You may not be able to use Plenaxis, or you may require a dosage adjustment or special monitoring during treatment.

Plenaxis is not intended for use by women. Plenaxis is in the FDA pregnancy category X. This means that Plenaxis will cause birth defects in an unborn baby. Do not use this medication if you are pregnant or if you could become pregnant during treatment. Plenaxis is not intended for use by women. It is not known whether Plenaxis passes into breast milk. Do not use this medication without first talking to your doctor if you are breast-feeding a baby.

How should I use Plenaxis?

Plenaxis must be administered by a qualified healthcare provider.

Plenaxis is administered as an injection into the muscle.

In some cases, the use of Plenaxis has resulted in serious allergic reactions. An allergic reaction may occur after any injection of the medication, including, but not limited to the first dose. Patients should be observed in the doctor's office for at least 30 minutes following each dose so that immediate treatment of an allergic reaction can be obtained if needed.

Treatment with Plenaxis may become less effective over time in some patients. Monitoring blood levels of testosterone will be done on a regular basis with blood tests to monitor the effectiveness of the medication.

It is important to use Plenaxis regularly to get the most benefit.

Plenaxis vials for injection should be stored at room temperature away from moisture and heat.