Plerixafor
Generic name: plerixafor [ pler-IX-a-fore ]
Brand name: Mozobil
Dosage form: subcutaneous solution (20 mg/mL)
Drug classes:Hematopoietic stem cell mobilizer, Other immunostimulants
What is plerixafor?
Plerixafor is used in people with non-Hodgkin's lymphoma or multiple myeloma.
Plerixafor helps your bone marrow release stem cells into your bloodstream so they can be collected and transplanted back into your body.
Plerixafor may also be used for purposes not listed in this medication guide.
Warnings
Do not use if you are pregnant. Use effective birth control, and tell your doctor if you become pregnant during treatment.
Before taking this medicine
You should not be treated with plerixafor if you are allergic to it, or if you have leukemia.
Tell your doctor if you have kidney disease.
Plerixafor may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using plerixafor and for at least 1 week after your last dose. Tell your doctor if you become pregnant.
You may need to have a negative pregnancy test before starting this treatment.
You should not breastfeed while receiving this medication.
How is plerixafor given?
Plerixafor is injected under the skin. A healthcare provider will give you this injection.
You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction.
Before receiving plerixafor, you will be given a medication called a granulocyte (GRAN-yoo-loe-site) colony stimulating factor (G-CSF). A G-CSF helps your body produce stem cells and white blood cells to help support your immune system.
Plerixafor works together with the G-CSF by causing stem cells and granulocytes produced in the bone marrow to circulate into your bloodstream where they can be collected in blood drawn from your vein.
After your blood is drawn, it will be processed so that the needed stem cells and granulocytes can be separated from other unneeded parts of the blood. These stem cells and granulocytes will then be "transplanted" back into your body.
Your blood will need to be tested often during your treatment.
