Plerixafor (Subcutaneous)
Medically reviewed by Drugs.com. Last updated on Apr 7, 2022.
Commonly used brand name(s)
In the U.S.
- Mozobil
Available Dosage Forms:
- Solution
Therapeutic Class: Hematopoietic
Uses for plerixafor
Plerixafor injection is used together with a granulocyte-colony stimulating factor or G-CSF (eg, filgrastim, pegfilgrastim) to mobilize hematopoietic stem cells (HSC) for collection and transplantation in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma (MM).
Plerixafor is to be given only by or under the direct supervision of your doctor.
Before using plerixafor
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For plerixafor, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to plerixafor or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of plerixafor injection in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of plerixafor injection in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment in the dose for patients receiving plerixafor.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of plerixafor. Make sure you tell your doctor if you have any other medical problems, especially:
- Bone marrow cancer or other bone marrow problems (eg, leukemia) or
- Enlarged spleen or
- Leukocytosis (high white blood cell count) or
- Thrombocytopenia (low blood platelet count)—Use with caution. May make these conditions worse.
- Kidney disease, moderate or severe—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
