Acetaminophen, chlorpheniramine, dextromethorphan, and pseudoephedrine

Generic name: acetaminophen, chlorpheniramine, dextromethorphan, and pseudoephedrine [ a-SEET-a-MIN-oh-fen, KLOR-fen-EER-a-meen, DEX-troe-meth-OR-fan, SOO-doe-ee-FED-rin ]
Brand names: Comtrex Cold and Flu Maximum Strength Tablet, Robitussin Flu, Theraflu (pseudoephedrine) Cold & Cough, Theraflu Flu & Cough, Theraflu Severe Cold & Congestion, ... show all 36 brands Triaminic Cold and Fever, Vicks 44 Cold, Flu and Cough, Tylenol Cold and Flu Powder, Theraflu Flu, Cold and Cough Powder, Theraflu Nighttime Maximum Strength, Comtrex Day and Night, Theraflu Night Cough and Cold and Flu, Co-Apap, Vicks Formula 44M, Cough Formula M Multi-Symptom, Vicks 44 Cold, Flu and Cough, Mapap Cold, Child Tylenol Cold Multi-Symptom Plus Cough, Comtrex Cold and Flu Maximum Strength Liquid, Genacol Maximum Strength, Robitussin Honey Flu Nighttime, Children's Tylenol Flu, Alka-Seltzer Plus Cough and Cold Liquigel, Tylenol Cold Complete Formula, Children's Tylenol Cold Plus Cough, Contac Cold and Flu Maximum Strength, Triaminic Flu, Cough and Fever, Theraflu (pseudoephedrine) Cold/Cough, Theraflu Severe Cold and Congestion, Theraflu Flu and Cough, Tylenol Cold Day/Night Convenience Pack, Tylenol Cold + Flu Multi-Action Day/Night Extra Strength
Dosage forms: oral capsule (325 mg-2 mg-15 mg-30 mg); oral liquid (160 mg-1 mg-5 mg-15 mg/5 mL); oral powder for reconstitution (1000 mg-4 mg-30 mg-60 mg; 650 mg-4 mg-20 mg-60 mg); oral tablet (500 mg-2 mg-15 mg-30 mg); oral tablet, chewable (80 mg-0.5 mg-2.5 mg-7.5 mg)
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com on Jul 12, 2021. Written by Cerner Multum.

What is acetaminophen, chlorpheniramine, dextromethorphan, and pseudoephedrine?

Acetaminophen is a pain reliever and fever reducer. Chlorpheniramine is an antihistamine. Dextromethorphan is a cough suppressant. Pseudoephedrine is a decongestant.

Acetaminophen, chlorpheniramine, dextromethorphan, and pseudoephedrine is a combination medicine used to treat headache, fever, body aches, cough, sore throat, runny or stuffy nose, sneezing, or sinus pressure caused by the flu or common cold.

Acetaminophen, chlorpheniramine, dextromethorphan, and pseudoephedrine may also be used for purposes not listed in this medication guide.

Warnings

Do not use this medicine if you have used an MAO inhibit