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Podofilm Topical
  • Treatments
  • Human Papilloma Virus
  • Podofilm (Topical)

Podofilm (Topical)

Generic name: podophyllum resin (topical route) [ pode-oh-FIL-um-REZ-in ]
Drug class:Topical keratolytics

Medically reviewed by Drugs.com. Last updated on Jan 24, 2022.

Commonly used brand name(s)

In Canada

  • Podofilm

Uses for Podofilm

Podophyllum is used to remove benign (not cancer) growths, such as certain kinds of warts. It works by destroying the tissue of the growth.

A few hours after podophyllum is applied to a wart, the wart becomes blanched (loses all color). In 24 to 48 hours, the medicine causes death of the tissue. After about 72 hours, the wart begins to slough or come off and gradually disappears.

Podophyllum is usually applied only in a doctor's office because it is a poison and can cause serious side effects if not used properly. However, your doctor may ask you to apply this medicine at home. If you do apply it at home, be sure you understand exactly how to use it.

Podophyllum is available only with your doctor's prescription.

Before using Podofilm

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Although there is no specific information comparing use of topical podophyllum in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of topical podophyllum in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Crumbling or bleeding warts or warts that have recently had surgery on t...