Polocaine Injection
Generic name: mepivacaine hydrochloride
Dosage form: injection, solution
Drug class:Local injectable anesthetics
Medically reviewed by Drugs.com. Last updated on Jul 1, 2021.
Rx Only
THESE SOLUTIONS ARE INTENDED FOR DENTAL USE ONLY.
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Polocaine Injection Description
Mepivacaine Hydrochloride, a tertiary amine used as a local anesthetic, is 1-methyl-2,' 6' - pipecoloxylidide monohydrochloride with the following structural formula:
It is a white, crystalline, odorless powder soluble in water, but very resistant to both acid and alkaline hydrolysis.
Levonordefrin, a sympathomimetic amine used as a vasoconstrictor in local anesthetic solution, is (-)-α-(1-Aminoethyl)-3, 4-dihydroxybenzyl alcohol with the following structural formula:
It is a white or buff-colored crystalline solid, freely soluble in aqueous solutions of mineral acids, but practically insoluble in water.
DENTAL CARTRIDGES MAY NOT BE AUTOCLAVED.
3% (30 mg/mL) Polocaine® DENTAL (mepivacaine hydrochloride injection 3% (30 mg/mL)) and 2% (20 mg/mL) Polocaine® DENTAL with Levonordefrin 1:20,000 (mepivacaine hydrochloride 2% (20 mg/mL) with levonordefrin 1:20,000 injection) are sterile solutions for injection.
| COMPOSITION: | CARTRIDGE | |
|---|---|---|
| The pH of the 2% cartridge solution is adjusted between 3.3 and 5.5 with NaOH. | ||
| The pH of the 3% cartridge solution is adjusted between 4.5 and 6.8 with NaOH. | ||
| Each mL contains: | 2% |
MEDICAL DEPARTMENTS
Cardiology
Pediatrics
Diabetes Care
Pre-natal Care
Ultrasound Echocardiogram
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