Poly Hist CB

Generic name:carbetapentane citrate and guaifenesin
Dosage form: liquid
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Poly Hist CB

Antitussive/Expectorant
Rx Only

Description: Poly Hist CB is an alcohol-free, sugar-free, purple liquid for oral administration
having a grape odor and flavor.

Each Teaspoon (5 mL) Contains:
CARBETAPENTANE CITRATE..... 20 mg
GUAIFENESIN .....75 mg

Poly Hist CB Liquid also contains: FD and C Blue #1, FD and C Red #40, Grape Flavor, Maltitol,
Propylene Glycol, Sodium Saccharin, Sorbitol, Purified Water.

Clinical Pharmacology:

Carbetapentane citrate is a centrally acting non-narcotic antitussive.

Guaifenesin is an expectorant. Its action increases the output of respiratory tract fluid by reducing
adhesiveness and surface tension. Sinus and bronchial drainage is improved and dry, nonproductive
coughs become more productive and less frequent.

Indications And Usage:

for temporary relief of non-productive cough accompanying respiratory tract congestion associated with
the common cold, influenza, sinusitis, and bronchitis.

Contraindications:

Poly Hist CB is contraindicated in infants and newborns, and in patients with a known
hypersensitivity to any of the components. It is also contraindicated in patients on MAO inhibitor therapy.

Warnings:

A persistent cough may be a sign of a serious condition. If cough persists for more than one week
or tends to recur, or is accompanied by fever, rash, or persistent headache, patient reevaluation
should be considered.

Precautions:

DRUG INTERACTIONS: Guaifenesin may produce an increase in urinary 5-hydroxy-indoleacetic acid and
may therefore interfere with the interpretation of this test for the diagnosis of carcinoid syndrome. It may
also falsely elevate the VMA test for catechols. Administration of this drug should be discontinued 48 hours
prior to the collection of urine specimens for suc