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Pralidoxime
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Pralidoxime

Generic name: pralidoxime [ PRAL-i-DOX-eem ]
Brand name: Protopam Chloride
Dosage form: intravenous powder for injection (1 g)
Drug class:Antidotes

Medically reviewed by Drugs.com on Jun 28, 2021. Written by Cerner Multum.

What is pralidoxime?

Pralidoxime is used as an antidote to treat poisoning caused by chemicals, pesticides (insect sprays), or drugs used to treat a muscle disorder.

This medication is not effective as an antidote for all types of pesticide poisonings.

Pralidoxime may also be used for purposes not listed in this medication guide.

Warnings

If you receive pralidoxime during an emergency, make sure any follow-up doctor knows you received pralidoxime.

Before taking this medicine

If possible during an emergency, tell your caregivers if you've ever had:

If possible during an emergency, tell your caregivers if you are pregnant or breastfeeding.

How is pralidoxime given?

Pralidoxime is injected into a muscle, under the skin, or into a vein.

Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely.

You may be watched for up to 72 hours to make sure the medicine has been effective and you no longer have any effects of the poison.

What happens if I miss a dose?

In a medical setting you are not likely to miss a dose.

What happens if I overdose?

In a medical setting an overdose would be treated quickly.

What should I avoid after receiving pralidoxime?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Pralidoxime side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some of the side effects of pralidoxime may be similar to the symptoms of poisoning. Your caregivers will watch you closely to determine whether your body is respondin...