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Praluent
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Praluent

Generic name:alirocumabAL-i-ROK-ue-mab ]
Brand names: Praluent Pen, Praluent Syringe
Drug class:PCSK9 inhibitors

Medically reviewed by Judith Stewart, BPharm. Last updated on Nov 2, 2021.

What is Praluent?

Praluent is a human monoclonal antibody. It works by helping the liver reduce levels of "bad" cholesterol (low-density lipoprotein, or LDL) circulating in your blood.

Praluent is used in adults with heart disease to reduce the risk of heart attack, stroke, and certain types of chest pain conditions (unstable angina) requiring hospitalization.

Praluent is used together with a low-fat diet, alone or together with other cholesterol-lowering medicines in adults with high blood cholesterol levels called primary hyperlipidemia (including a type of high cholesterol called heterozygous familial hypercholesterolemia), an inherited type of high cholesterol. This condition can cause high blood levels of LDL cholesterol, and can also cause plaque to build up inside your arteries.

Praluent is also used along with other LDL-lowering treatments in adults with a type of high cholesterol called homozygous familial hypercholesterolemia, who need additional lowering of LDL-C.

Warnings

Use Praluent only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not use Praluent if you are allergic to alirocumab.

Not approved for use by anyone younger than 18 years old.

It is not known if alirocumab will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of alirocumab on the baby.

It is not known whether alirocumab passes into breast milk or if it could harm a nursing baby...