Pramoxine
Class: Antipruritics and Local Anesthetics
ATC Class: D04AB07
VA Class: DE700
CAS Number: 637-58-1
Brands: Analpram, Analpram HC, Campho-Phenique Cold Sore, Fleet Pain-Relief, Itch-X, PrameGel, Preparation H, Proctofoam, Vagisil Medicated
Introduction
Local anesthetic.
Uses for Pramoxine
Dermatologic Conditions
Self-medication for the temporary relief of pain and itching associated with minor lip or skin irritations (e.g., dermatoses, insect bites, minor burns or sunburns, minor cuts or scrapes, cold sores, hives, rashes due to poison ivy, poison oak, or poison sumac).
Anorectal/Anogenital Disorders
Self-medication for the temporary relief of pain, soreness, burning, itching, or discomfort associated with hemorrhoids and other anorectal or anogenital disorders (e.g., inflammation, irritation, fissures, anogenital pruritus).
In fixed combination with hydrocortisone for relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses of the anal region.
Pramoxine Dosage and Administration
Administration
Topical
Apply topically to the skin as a gel, lotion, ointment, or solution.
Apply topically to the lip as an ointment.
Do not use topical skin preparations for vaginal, genital, or rectal itching.
For external use only; avoid contact with the eyes and nose. Do not apply to extensive areas of skin, open wounds, or damaged or blistered skin; do not use for prolonged periods.
Do not use on deep or puncture wounds, animal bites, or serious burns.
Apply to cold sores and fever blisters after blister has dried.
Shake lotion well before use.
Anorectal Topical Administration
Apply externally to the anorectal area as an aerosol foam, cream, ointment, lotion, or pledgets. Do not insert drug into rectum using fingers or any mechanical device.
Before applying drug, cleanse the affected perianal area with mild soap and warm water and rinse thoroughly whenever practical; dry by patting or blotting with toilet tissue or a soft cloth.
Shake aerosol foam before use. Disperse onto a clean tissue before applying to the affected area. Rub in gently. Do not insert any part of the aerosol container past anus into the rectum. Clean applicator thoroughly after each use.
Apply pledget by gently patting the affected area with pledget; use pledget only once, then discard.
Vaginal Topical Administration
Apply externally to vaginal area as vaginal pledgets.
Apply by gently patting or wiping the affected area from front to back; use pledget only once, then discard.
Anal Administration
Apply topically to anus as an aerosol foam.
In fixed combination with hydrocortisone: Apply aerosol foam using provided applicator for anal administration.
Shake aerosol foam before use. Do not insert any part of the aerosol container past anus into the rectum. Clean applicator thoroughly after each use.
