Acetaminophen, dextromethorphan, and doxylamine

Generic name: acetaminophen, dextromethorphan, and doxylamine [ a-SEET-a-MIN-oh-fen, DEX-tro-me-THOR-fan, and-dox-IL-a-meen ]
Brand names: All-Nite, Contac Cold+Flu Cooling Night, Coricidin HBP Nighttime Multi-Symptom Cold, Night Time Cold/Flu, Nyquil Cold & Flu, ... show all 27 brands Robitussin Peak Cold Nighttime Cold + Flu, Tylenol Cold & Cough Nighttime Cool Burst, Tylenol Warming Cough & Sore Throat Nightime, Tylenol Cough & Sore Throat Nightime, Tylenol Cough and Sore Throat Night Time, NyQuil Cold/Flu Relief Cherry, NyQuil Cold/Flu Relief, Nyquil Cold and Flu, NiteTime Cold and Flu, Tylenol Warming Cough and Sore Throat Nighttime, Cough and Sore Throat Nighttime, Delsym Cough-Cold Nighttime, Sunmark Nite Time Cold and Flu, Tylenol Cold and Cough Nighttime Cool Burst, Delsym Nighttime Cough and Cold, Multi-Symptom Nighttime Cold and Flu Relief, Multi-Symptom Nighttime Cold and Flu Relief (cherry), Nyquil Cold and Flu Nighttime, NyQuil Nature Fusion Cold and Flu Nighttime, NightTime Cold and Flu Cherry, NightTime Cold and Flu, Cold and Flu Nighttime Relief
Dosage forms: oral capsule (325 mg-15 mg-6.25 mg); oral liquid (1000 mg-30 mg-12.5 mg/30 mL; 325 mg-15 mg-6.25 mg/15 mL; 500 mg-15 mg-6.25 mg/15 mL; 650 mg-30 mg-12.5 mg/30 mL)
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com on Oct 11, 2021. Written by Cerner Multum.

What is acetaminophen, dextromethorphan, and doxylamine?

Acetaminophen is a pain reliever and fever reducer.

Dextromethorphan is a cough suppressant. It affects the cough reflex in the brain that triggers coughing.

Doxylamine is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Acetaminophen, dextromethorphan, and doxylamine is a combination medicine used to treat headache, fever, body aches, cough, runny nose, sneezing, and sore throat caused by allergies, the common cold, or the flu.

acetaminophen, dextromethorphan, and doxylamine will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen, dextromethorphan, and doxylamine may also be used for purposes not listed in this medication guide.