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PrandiMet
  • Treatments
  • Diabetes
  • Type 2

PrandiMet

Generic name:metformin and repaglinidemet-FOR-min-and-re-PAG-li-nide ]
Drug class:Antidiabetic combinations

Medically reviewed by Philip Thornton, DipPharm. Last updated on Sep 21, 2021.

What is PrandiMet?

PrandiMet contains a combination of metformin and repaglinide. Metformin and repaglinide are both oral diabetes medicines that help control blood sugar levels. Repaglinide works by causing the pancreas to produce insulin. Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines.

PrandiMet is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

PrandiMet is not for treating type 1 diabetes.

Warnings

You should not use PrandiMet if you have severe kidney disease, type 1 diabetes, or diabetic ketoacidosis.

You should not use PrandiMet together with gemfibrozil or NPH insulin (such as isophane insulin).

If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking PrandiMet.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.

Before taking this medicine/h2>

You should not use PrandiMet if you are allergic to metformin or repaglinide, or if you have:

  • severe kidney disease;

  • diabetic ketoacidosis (call your doctor for treatment); or

  • if you also use gemfibrozil or NPH insulin (such as isophane insulin).

If you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking PrandiMet. Be sure your caregivers know ahead of time that you are using this medicine.

Tell your doctor if you have ever had:

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.

Follow your doctor's instructions about using PrandiMet if you are pregnant. Blood sugar control is very impor...