Aprepitant
Generic name: aprepitant (oral/injection) [ a-PREP-i-tant ]
Brand names: Cinvanti, Emend, Emend 3-Day, Emend 2-Day
Dosage forms: intravenous emulsion (130 mg/18 mL); oral capsule (125 mg; 40 mg; 80 mg); oral kit (125 mg-80 mg); oral powder for reconstitution (125 mg)
Drug class:NK1 receptor antagonists
What is aprepitant?
Aprepitant is used together with other medications to prevent nausea and vomiting that may be caused by chemotherapy.
Aprepitant is given ahead of time and will not treat nausea or vomiting that you already have.
Aprepitant capsules are for use in adults and children who are at least 12 years old. Aprepitant oral suspension (liquid) can be given to adults and children as young as 6 months old.
Aprepitant may also be used for purposes not listed in this medication guide.
Warnings
You should not use aprepitant if you also use pimozide. A serious drug interaction can occur when pimozide is used together with aprepitant.
Before taking this medicine
You should not use aprepitant if you are allergic to it, or if you use another medicine called pimozide. Aprepitant can cause unwanted or dangerous side effects when used with pimozide.
Tell your doctor if you have ever had:
Tell your doctor if you are pregnant or breastfeeding. You should not be treated with aprepitant injection if you are pregnant.
Aprepitant can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. To prevent pregnancy while using aprepitant, use a barrier form of birth control: condom, diaphragm, cervical cap, or contraceptive sponge.
Keep using the barrier form of birth control for 1 month after your last dose of aprepitant.
How should I use aprepitant?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Aprepitant oral is taken by mouth.
Aprepitant injection is given as an infusion into a vein. A healthcare provider will give you this injection.
Aprepitant is not for long-term use. You will most likely need only 1 to 3 doses.
The first dose of aprepitant is usually given 30 to 60 minutes before tr...
