Class: Corticosteroids
ATC Class: S02BA03
VA Class: OP300
Chemical Name: 11ß,17,21-trihydroxypregna-1,4-diene-3,20-dione
Molecular Formula: C21H28O5
CAS Number: 52-21-1
Brands: AK-Pred, Econopred, Inflamase, Pred
Introduction
A synthetic nonfluorinated corticosteroid.
Uses for prednisoLONE (EENT)
Ophthalmic Inflammation
Symptomatic relief of corticosteroid-responsive allergic and inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe (e.g., allergic or vernal conjunctivitis, acne rosacea keratitis, superficial punctate keratitis, herpes zoster keratitis, uveitis, iritis, cyclitis).
Treatment of corneal, conjunctival, and scleral injuries from chemical, radiation, or thermal burns or penetration of foreign bodies.
Bacterial Ophthalmic Infections
Used for anti-inflammatory properties in conjunction with appropriate anti-infective therapy in some bacterial infections of the eye; used in fixed combination with gentamicin sulfate, sulfacetamide sodium, or the combination of neomycin sulfate and polymyxin b sulfate when such combination therapy is indicated. If an ophthalmic corticosteroid is used in combination with an ophthalmic anti-infective, weigh benefits against risks. (See Infections under Cautions.)
prednisoLONE (EENT) Dosage and Administration
Administration
Ophthalmic Administration
Apply topically to the eyes as an ophthalmic ointment, solution, or suspension.
Not for injection.
Shake suspension well prior to each use.
Avoid contamination of the preparation container.
May use ointment at night in conjunction with daytime use of a suspension or solution to reduce the frequency of applications required with the liquid dosage forms.
To treat eyelids, instill into the eye, then close the eye ...