Premarin Vaginal
Generic name:conjugated estrogens (vaginal route) [ KON-joo-gay-ted-ES-troe-jenz ]
Drug classes:Estrogens, Miscellaneous vaginal agents
Medically reviewed by Drugs.com. Last updated on Mar 8, 2022.
Endometrial Cancer, Cardiovascular Disorders, Breast Cancer and Probable DementiaEstrogen-Alone TherapyThere is an increased risk of endometrial cancer in a woman with a uterus who uses unopposed estrogens.Estrogen-alone therapy should not be used for the prevention of cardiovascular disease or dementia.Women's Health Initiative estrogen-alone substudy reported increased risks of stroke and deep vein thrombosis.The Women’s Health Initiative Memory Study estrogen-alone ancillary study of Women’s Health Initiative reported an increased risk of probable dementia in postmenopausal women 65 years of age and older.Estrogen Plus Progestin TherapyEstrogen plus progestin therapy should not be used for the prevention of cardiovascular disease or dementia.The Women’s Health Initiative estrogen plus progestin substudy reported increased risks of stroke, DVT, pulmonary embolism, and myocardial infarction.The Women’s Health Initiative estrogen plus progestin substudy reported increased risks of invasive breast cancer.The Women’s Health Initiative Memory Study estrogen plus progestin ancillary study of Women’s Health Initiative reported an increased risk of probable dementia in postmenopausal women 65 years of age and older .
Commonly used brand name(s)
In the U.S.
- Premarin
- Premarin Vaginal
Available Dosage Forms:
- Cream
Therapeutic Class: Female Reproductive Agent
Pharmacologic Class: Estrogen
Uses for Premarin Vaginal
Conjugated estrogens is a medicine that contains a mixture of estrogen hormones. Conjugated estrogens vaginal cream is used to treat changes in and around the vagina (such as vaginal dryness, itching, and burning) caused by low estrogen levels or menopause. It is also used to treat vaginal pain during sexual intercourse.
This medicine is available only with your doctor's prescription.
Before using Premarin Vaginal
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Use of Premarin® vaginal cream is not indicated for children.
Geriatric
Although appropriate studies on the relationship of age to the effects of Premarin® vaginal cream have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have breast cancer, stroke, or dementia, which may require caution in patients receiving this medicin..
