Aptivus

Generic name:tipranavir [ tip-RA-na-veer ]
Drug class:Protease inhibitors

Medically reviewed by Philip Thornton, DipPharm. Last updated on Dec 1, 2021.

What is Aptivus?

Aptivus is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body.

Aptivus is used together with another drug called ritonavir to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS).

Aptivus is not a cure for HIV or AIDS.

Warnings

You should not use Aptivus if you have moderate to severe liver disease.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

Some people taking Aptivus with ritonavir have developed fatal medical problems including liver damage and bleeding in the brain. Stop taking these medicines and get emergency medical attention if you have: right-sided upper stomach pain, nausea, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes), unusual bleeding, sudden severe headache, or problems with speech or vision.

Before taking this medicine

You should not use Aptivus if you are allergic to tipranavir, or if you have:

• moderate to severe liver disease.

Some medicines can cause unwanted or dangerous effects when used with Aptivus. Your doctor may change your treatment plan if you also use:

• alfuzosin;

• cisapride;

• lurasidone;

• pimozide;

• rifampin;

• sildenafil (Revatio for pulmonary arterial hypertension);

• St. John's wort;

• ergot medicine - dihydroergotamine, ergotamine, ergonovine, methylergonovine;

• heart medication - amiodarone, flecainide, propafenone, quinidine;

• a sedative - oral midazolam, triazolam; or

• "statin" cholesterol medicine - atorvastatin, lovastatin, simvastatin.

Tell your doctor if you have ever had:

• live...