Probenecid and colchicine (Oral)

Medically reviewed by Drugs.com. Last updated on Mar 17, 2022.

Available Dosage Forms:

• Tablet

Therapeutic Class: Antigout

Uses for probenecid and colchicine

Probenecid and colchicine combination is used to treat gout or gouty arthritis.

The probenecid in probenecid and colchicine helps to prevent gout attacks by removing extra uric acid from the body. The colchicine in probenecid and colchicine also helps to prevent gout attacks. Although colchicine may also be used to relieve an attack of gout, this requires more colchicine than this combination medicine contains. Probenecid and colchicine combination does not cure gout. Probenecid and colchicine will help prevent gout attacks only as long as you continue to take it.

Probenecid and colchicine combination is available only with your doctor's prescription.

Before using probenecid and colchicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For probenecid and colchicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to probenecid and colchicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on this combination medicine have been done only in adult patients, and there is no specific information about its use in children.

Geriatric

Elderly people are especially sensitive to the effects of colchicine. This may increase the chance of side effects during treatment.

There is no specific information comparing use of probenecid in the elderly with use in other age groups.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking probenecid and colchicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using probenecid and colchicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

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