Procto-kit

Generic name: hydrocortisone acetate
Dosage form: cream
Drug class:Topical steroids

Medically reviewed by Drugs.com. Last updated on Jan 1, 2021.

FOR TOPICAL USE ONLY.

Rx only

Procto-kit Description

Hydrocortisone is a synthetic steroid used as an anti-inflammatory and antipruritic agent. Its chemical name is Pregn-4-ene-3,20-dione, 11,17,21- trihydroxy-, (11β)- with empirical formula as C21H30O5 and molecular weight 362.47. Its structural formula is:

Proctosol-HC® 2.5% (Hydrocortisone Cream USP, 2.5%) (Each gram contains 25 mg of Hydrocortisone) in a base containing cetyl alcohol, isopropyl palmitate, methylparaben, mineral oil and lanolin alcohol, polyoxyl 40 stearate, polysorbate 60, propylene glycol monostearate, propylene glycol, propylparaben, purified water, sorbic acid, and sorbitan monostearate.

Procto-kit - Clinical Pharmacology

Topical corticosteroids share anti-inflammatory, anti-pruritic and vasoconstrictive actions.

The mechanism of anti-inflammatory activity of topical corticosteroids is unclear. Various laboratory methods, including vasoconstrictor assays, are used to compare and predict potencies and/or clinical efficacies of the topical corticosteroids. There is som...