Abacavir, lamivudine, and zidovudine
Generic name: abacavir, lamivudine, and zidovudine [ a-BACK-a-veer, la-MIV-yoo-deen, zye-DOE-vyoo-deen ]
Brand name: Trizivir
Dosage form: oral tablet (300 mg-150 mg-300 mg)
Drug class:Antiviral combinations
What is abacavir, lamivudine, and zidovudine (Trizivir)?
Abacavir, lamivudine, and zidovudine are antiviral medications that prevent human immunodeficiency virus (HIV) from multiplying in your body.
Abacavir, lamivudine, and zidovudine (Trizivir) is a combination medicine used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). abacavir, lamivudine, and zidovudine is not a cure for HIV or AIDS.
Trizivir may also be used for purposes not listed in this medication guide.
Warnings
You should not take this medicine if you have ever had an allergic reaction to any medicine that contains abacavir, or if you have a gene variation called HLA-B*5701 allele. Also, you should not use this medicine if you have moderate or severe liver disease.
Stop taking this medicine and call your doctor at once if you have signs of an allergic reaction: fever; rash; nausea, vomiting, diarrhea, stomach pain; general ill feeling, extreme tiredness, body aches; shortness of breath, cough, sore throat.
If you've ever had hepatitis B, it may become active or get worse after you stop using Trizivir. You may need frequent liver function tests for several months.
Before taking this medicine
You should not use Trizivir if you are allergic to abacavir, lamivudine, or zidovudine, or if:
you have moderate or severe liver disease;
you have a gene variation called HLA-B*5701 allele (your doctor will test you for this); or
you have a history of allergic reaction to Combivir, Epivir, Epzicom, Retrovir, or Ziagen.
You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, if you've taken HIV medication for a long time, or if you are a woman. Ask your doctor about your risk.
Tell your doctor if you have ever had:
liver disease (...
