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Prograf
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Prograf

Generic name:tacrolimus (oral/injection) [ ta-KROE-li-mus ]
Drug class:Calcineurin inhibitors

Medically reviewed by Judith Stewart, BPharm. Last updated on Sep 7, 2021.

What is Prograf?

Prograf weakens your body's immune system, to help keep it from "rejecting" a transplanted organ such as a kidney. Organ rejection happens when the immune system treats the new organ as an invader and attacks it.

Prograf is a prescription medicine and is used together with other medicines to prevent your body from rejecting a heart, liver, lung, or kidney transplant.

Prograf is supplied as oral capsules, granules for oral suspension, and as an injection for intravenous use.

Prograf capsules and oral granules are immediate-release medicines and they are not the same as tacrolimus extended-release tablets or tacrolimus extended-release capsules. Your healthcare provider should decide what medicine is right for you.

Warnings

Prograf may increase your risk of developing a serious infection, lymphoma, or other cancers. Talk with your doctor about the risks and benefits of using this medicine.

Call your doctor right away if you have any signs of infection such as fever, chills, flu symptoms, cough, sweating, painful skin sores, skin warmth or redness, or muscle aches.

You will need regular medical tests to be sure Prograf is not causing harmful effects. Do not miss any follow up visits to your doctor for blood or urine tests. Avoid being near people who are sick or have infections.

Call your doctor right away if you have symptoms of a serious brain infection, such as a change in your mental state, problems with speech or walking, or decreased vision. These symptoms may start gradually and get worse quickly.