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Promethazine Syrup
  • Professionals
  • FDA PI

Promethazine Syrup

Generic name: promethazine hydrochloride
Dosage form: oral syrup
Drug classes:Antihistamines, Phenothiazine antiemetics

Medically reviewed by Drugs.com. Last updated on Oct 1, 2021.

Promethazine Syrup Description

Each teaspoonful (5 mL) of Promethazine Hydrochloride Syrup (Promethazine Hydrochloride Oral Solution, USP) contains 6.25 mg promethazine HCl in a flavored syrup base with a pH between 4.9 and 5.4. Alcohol 8%(v/v). The inactive ingredients present are: anhydrous citric acid, ascorbic acid, D&C yellow No. 10, edetate disodium, FD&C blue No. 1 powder, FD&C red No. 40, glycerin, methylparaben, natural and artificial strawberry banana flavor, natural fruit punch flavor, purified water, sodium benzoate, sodium citrate, sodium propionate, sodium saccharin, and sucrose.

Promethazine hydrochloride is a racemic compound; the empirical formula is C17H20N2S•HCl and its molecular weight is 320.88.

Promethazine hydrochloride, a phenothiazine derivative, is designated chemically as 10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-, monohydrochloride, (±)- with the following structural formula:

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