Promethegan (Rectal)
Generic name:promethazine (rectal route) [ proe-METH-a-zeen ]
Drug classes:Antihistamines, Phenothiazine antiemetics
Medically reviewed by Drugs.com. Last updated on May 7, 2022.
Promethazine hydrochloride should not be used in pediatric patients less than 2 years of age because of the potential for fatal respiratory depression. Postmarketing cases of respiratory depression, including fatalities, have been reported with use of promethazine hydrochloride in pediatric patients less than 2 years of age. A wide range of weight-based doses of promethazine hydrochloride have resulted in respiratory depression in these patients. Caution should be exercised when administering promethazine hydrochloride to pediatric patients 2 years or age and older. It is recommended that the lowest effective dose of promethazine hydrochloride be used in pediatric patients 2 years of age and older and concomitant administration of other drugs with respiratory depressant effects be avoided .
Commonly used brand name(s)
In the U.S.
- Phenadoz
- Phenergan
- Promethegan
Available Dosage Forms:
- Suppository
Therapeutic Class: Gastrointestinal Agent
Pharmacologic Class: Antihistamine
Chemical Class: Aliphatic
Uses for Promethegan
Promethazine is used to relieve or prevent the symptoms of hay fever, allergic conjunctivitis (inflammation of the eye), and other types of allergy or allergic reactions. It works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. It can sometimes close up the bronchial tubes (air passages of the lungs) and make breathing difficult .
Promethazine is also used to prevent and control motion sickness, nausea, vomiting, and dizziness. In addition, it may be used to help people go to sleep and control their pain or anxiety before or after surgery or other procedures .
Promethazine may also be used for other conditions as determined by your doctor .
This medicine is only available with your doctor's prescription .
Before using Promethegan
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of promethazine in the pediatric population. Safety and efficacy have not been established in children below 2 years of age. Caution should be used when this medicine is given to children 2 years of age and older .
Geriatric
Insufficient information is available on t..
