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Acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine
  • Treatments
  • Cold Symptoms

Acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine

Generic name: acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine [ a-SEET-a-MIN-o-fen, DEX-troe-meth-OR-fan, dox-IL-a-meen, SOO-doe-e-FED-rin ]
Brand names: NyQuil D, Nyquil Hot Therapy, All-Nite Cold, Nyquil Cold Medicine, Nyquil Liquicap, ... show all 14 brands
Dosage form: oral liquid (1000 mg-30 mg-12.5 mg-60 mg/30 mL)
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com on Feb 16, 2022. Written by Cerner Multum.

What is acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine?

Acetaminophen is a pain reliever and fever reducer.

Dextromethorphan is a cough suppressant. It affects the cough reflex in the brain that triggers coughing.

Doxylamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine is a combination medicine used to treat headache, fever, body aches, cough, runny nose, sneezing, and sinus congestion caused by the common cold, or the flu.

acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine may also be used for purposes not listed in this medication guide.

Warnings

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid,

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