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Pylera
  • Treatments
  • Helicobacter Pylori Infection

Pylera

Generic name:bismuth subcitrate potassium, metronidazole, and tetracyclineBIZ-muth-sub-SIT-rate-poe-TASS-ee-um, MET-roe-NYE-da-zole, TET-ra-SYE-kleen ]
Drug class:H. pylori eradication agents

Medically reviewed by Philip Thornton, DipPharm. Last updated on Oct 4, 2021.

What is Pylera?

Pylera contains a combination of bismuth subcitrate potassium, metronidazole, and tetracycline. Bismuth subcitrate potassium is a mineral. Metronidazole and tetracycline are antibiotics that fight bacteria in the body.

Pylera is used to treat peptic ulcer (duodenal ulcer) with Helicobacter pylori infection.

Pylera is usually given together with omeprazole (Prilosec).

Warnings

Do not use Pylera if you are pregnant or breastfeeding. Using tetracycline during pregnancy could harm the unborn baby or cause permanent tooth discoloration later in the baby's life.

Do not drink alcohol or consume foods or medicines that contain propylene glycol while you are taking Pylera and for at least 3 days after you stop taking it.

Avoid taking Pylera with milk or other dairy products. Also avoid taking the medicine at the same time you take any multivitamins, mineral supplements, or antacids. These products can make it harder for your body to absorb this medicine.

Metronidazole has caused cancer in animal studies. It is not known whether this would occur in humans taking Pylera.

Before taking this medicine

You should not use Pylera if...