Pyril D Suspension

Generic name:phenylephrine hydrochloride and pyrilamine maleate
Dosage form: oral suspension
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Rx Only

Pyril D Suspension Description

Pyril D Suspension is an antihistamine/ nasal decongestant combination for oral administration as a suspension. Each 5 mL (one teaspoonful) of the grape-flavored, purple-colored suspension for oral administration contains:

Inactive ingredients: Citric acid, FD&C Blue No. 1, FD&C Red No. 40, glycerin, grape flavor, magnesium aluminum silicate, methylparaben, purified water, sodium saccharin, sodium benzoate, sodium citrate dihydrate, sucrose, xanthan gum and galloquinate.

Pyril D Suspension - Clinical Pharmacology

Pyril D Suspension combines the sympathomimetic decongestant effect of phenylephrine with the antihistaminic action of pyrilamine.

PHENYLEPHRINE

Phenylephrine is a decongestant which is a potent postsynaptic α-receptor agonist with little effect on β receptors of the heart. A direct action at receptors accounts for the greater part of its effects, only a small part being due to its ability to release norepinephrine. Phenylephrine has no effect on β-adrenergic receptors of the bronchi or peripheral blood vessels.

Phenylephrine has a mild central stimulant effect.

PYRILAMINE

Pyrilamine is an antihistamine, H1 receptor b...