Radium ra 223 dichloride (Intravenous)

Medically reviewed by Drugs.com. Last updated on Mar 7, 2022.

Commonly used brand name(s)

In the U.S.

• Xofigo

Available Dosage Forms:

• Solution

Therapeutic Class: Radiopharmaceutical, Antineoplastic

Uses for radium ra 223 dichloride

Radium Ra 223 dichloride injection is used to treat men with castration-resistant (resistant to medical or surgical treatments to lower testosterone) prostate cancer that has spread to the bones but not to other organs. It is a radiopharmaceutical agent. Radiopharmaceuticals are radioactive agents that are used to find and treat certain diseases.

Radium ra 223 dichloride is to be given only by or under the direct supervision of your doctor.

Before using radium ra 223 dichloride

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For radium ra 223 dichloride, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to radium ra 223 dichloride or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of radium Ra 223 dichloride injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of radium Ra 223 dichloride injection in the elderly. However, elderly patients are more sensitive to the effects of radium ra 223 dichloride than younger adults.

Breastfeeding

Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using radium ra 223 dichloride.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving radium ra 223 dichloride, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using radium ra 223 dichloride with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Abiraterone Acetate

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems

The pre...