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Regranex
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Regranex

Generic name:becaplermin topicalbe-KAP-ler-min-TOP-ik-al ]
Drug class:Miscellaneous topical agents

Medically reviewed by Drugs.com on Sep 15, 2021. Written by Cerner Multum.

What is Regranex?

Regranex (for the skin) is used to treat diabetic foot ulcers in people with normal blood flow in the legs and feet.

Regranex is not for use in treating pressure ulcers (bed sores) or ulcers caused by poor circulation.

Regranex may also be used for purposes not listed in this medication guide.

Warnings

You should not use Regranex if you have cancer affecting the skin where you will apply this medicine.

Some people using becaplermin have developed cancer. However, it is not known whether this medicine actually causes cancer.

Before taking this medicine

You should not use becaplermin if you are allergic to it, or if you have cancer affecting the skin where you will apply Regranex.

Tell your doctor if you have ever had:

  • cancer; or

  • blood circulation problems in your lower legs.

Some people using becaplermin have developed cancer. However, it is not known whether becaplermin actually causes cancer. Ask your doctor about this risk.

Tell your doctor if you are pregnant or breastfeeding.

Regranex is not approved for use by anyone younger than 16 years old.

How should I use Regranex?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Do not take by mouth. Topical medicine is for use only on the skin.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Wash your hands before applying this medicine.

Use a cotton swab, tongue depressor, or other disposable applicator to apply Regranex to your skin.

To keep the tip of the medicine tube from getting contaminated, do not allow the tip to touch any surface, including your fingers or the ulcer you are treating.

It may take several weeks before your symptoms improve. Use this medicine daily and call your doctor if your foot ulcer is not at least one-third smaller in size after 10 weeks, or if it is not completely healed after 20 weeks.

Becaplermin is only part of a complete ulcer care program that includes not putting weight on your leg and foot that is affected by an ulcer. Follow your doctor's instructions very closely.

Your doctor will need to check your foot ulcer on a regular basis.

Store the medicine in a refrigerator. Do not freeze. Keep the tube tightly capped when not in use. Do not use Regranex past the expiration date.