Renacidin
Generic name:citric acid, gluconolactone and magnesium carbonate
Dosage form: irrigation
Drug class:Sterile irrigating solutions
Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.
On This Page
Renacidin Description
Renacidin® (Citric Acid, Glucono delta-lactone, and Magnesium Carbonate) is a sterile, non-pyrogenic irrigation solution for use within the lower urinary tract in the dissolution of bladder calculi of the struvite or apatite variety, and prevention of encrustations of urethral catheters and cystostomy tubes.
Each 30 mL of Renacidin contains:
Active ingredients:
Citric Acid (anhydrous), USP 1980.6 mg
C6H8O7
Glucono delta-lactone, USP 59.4 mg
C6H10O6
Magnesium Carbonate, USP 980.4 mg
(MgCO3)4 · Mg(OH)2 · 5H2O
Citric Acid
Glucono delta-lactone
Magnesium Carbonate
(MgCO3)4 · Mg(OH)2 · 5H2O
Inert ingredients:
Benzoic Acid, USP 6.9 mg
Solution pH: 3.85 (3.5-4.2)
Renacidin - Clinical Pharmacology
Renacidin's action on susceptible apatite calculi results from an exchange of magnesium from the irrigating solution for calcium contained in the stone matrix. The magnesium salts thereby formed are soluble in the gluconocitrate irrigating solution resulting in the dissolution of the calculus. Struvite calculi are composed mainly of magnesium ammonium phosphates which are solubilized by Renacidin due to its acidic pH. Renacidin is not effective for dissolution of calcium oxalate, uric acid or cysteine stones.
