Rinvoq
Generic name:upadacitinib [ ue-PAD-a-SYE-ti-nib ]
Drug class:Antirheumatics
What is Rinvoq?
Rinvoq is a prescription medicine that is a Janus kinase (JAK) inhibitor.
Rinvoq is used to treat:
- adults with moderate to severe rheumatoid arthritis when one or more medicines called tumor necrosis factor (TNF) blockers have been used, and did not work well or could not be tolerated.
- adults with active psoriatic arthritis when one or more medicines called tumor necrosis factor (TNF) blockers have been used, and did not work well or could not be tolerated.
- adults and children 12 years of age and older with moderate to severe eczema (atopic dermatitis) that did not respond to previous treatment and their eczema is not well controlled with other pills or injections, including biologic medicines, or the use of other pills or injections is not recommended.
- adults with moderate to severe ulcerative colitis when 1 or more medicines called tumor necrosis factor (TNF) blockers have been used, and did not work well or could not be tolerated.
- adults with active ankylosing spondylitis when 1 or more medicines called tumor necrosis factor (TNF) blockers have been used, and did not work well or could not be tolerated.
It is not known if Rinvoq is safe and effective in children under 18 years of age with juvenile idiopathic arthritis or with psoriatic arthritis.
It is not known if Rinvoq is safe and effective in children under 12 years of age with atopic dermatitis.
It is not known if Rinvoq is safe and effective in children with ulcerative colitis.
Rinvoq is available as:
- a 15 mg extended-release tablet. The tablets are purple, biconvex oblong and imprinted with ‘a15’ on one side.
- a 30 mg extended-release tablet. The tablets are red, biconvex oblong and imprinted with ‘a30’ on one side.
Warnings
Rinvoq affects your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, aches, tiredness, cough, skin sores, diarrhea, weight loss, or burning when you urinate.
Taking Rinvoq may increase your risk of life-threatening medical problems including serious infections, a hole or tear in your digestive tract, a heart attack or stroke, blood clots, or cancer.
Tell your doctor if you have a weak immune system, diabetes, chronic lung disease, or an infection such as hepatitis, tuberculosis, shingles, or HIV. Also tell your doctor if you've ever had ...
