Riociguat
Generic name: riociguat [ RYE-oh-SIG-ue-at ]
Brand name: Adempas
Dosage form: oral tablet (0.5 mg; 1 mg; 1.5 mg; 2 mg; 2.5 mg)
Drug class:Vasodilators
What is riociguat?
Riociguat is used to treat chronic thromboembolic pulmonary hypertension (CTEPH) in people who cannot be treated with surgery, or in people who have undergone surgery but still have symptoms. Riociguat can treat certain symptoms of CTEPH and can improve your ability to exercise.
Riociguat is also used to treat pulmonary arterial hypertension (PAH). Riociguat can improve your ability to exercise and help prevent PAH from getting worse.
Riociguat is available to women only under a special program. You must be registered in the program and understand the risks and benefits of riociguat.
Riociguat may also be used for purposes not listed in this medication guide.
Warnings
Riociguat can cause birth defects. Do not use if you are pregnant. You must use highly effective birth control while taking riociguat and for at least 1 month after your last dose. Do not have unprotected sex.
Before taking this medicine
You should not use riociguat if you are allergic to it, or if:
you are pregnant or might become pregnant during treatment; or
you have PAH related to a condition called idiopathic interstitial pneumonias (PH-IIP).
Some medicines can cause unwanted or dangerous effects when used with riociguat. Your doctor may change your treatment plan if you also use:
erectile dysfunction medicine such as Viagra, Cialis, Levitra, and others;
a nitrate drug for chest pain or heart problems (amyl nitrite, nitroglycerin, and others); or
Do not take riociguat within 24 hours before or after taking sildenafil (Revatio, Viagra), or within 24 hours before or 48 hours after taking tadalafil (Adcirca, Cialis).
Tell your doctor if you have ever had:
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