Medically reviewed by Drugs.com. Last updated on May 28, 2022.
Warning: Fatal Infusion Reactions, Severe Mucocutaneous Reactions, Hepatitis B Virus Reactivation, and Progressive Multifocal LeukoencephalopathyFatal infusion-related reactions within 24 hours of rituximab infusion; approximately 80% of fatal infusion reactions occurred with first infusion. Monitor patients and discontinue rituximab-pvvr infusion for severe reactions.Severe mucocutaneous reactions, some with fatal outcomesHepatitis B virus (HBV) reactivation, in some cases resulting in fulminant hepatitis, hepatic failure, and deathProgressive multifocal leukoencephalopathy (PML) resulting in death
Commonly used brand name(s)
In the U.S.
- Ruxience
Available Dosage Forms:
- Solution
Therapeutic Class: Antineoplastic Agent
Pharmacologic Class: Rituximab
Uses for rituximab-pvvr
Rituximab-pvvr injection is used alone or together with other cancer medicines to treat a type of cancer called non-Hodgkin's lymphoma (NHL). It helps the immune system destroy cancer cells. Rituximab-pvvr is a monoclonal antibody.
Rituximab-pvvr injection is also used together with other cancer medicines (eg, fludarabine and cyclophosphamide) to treat chronic lymphocytic leukemia (CLL).
Rituximab-pvvr injection is used together with steroids to treat granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). These are immune disorders that cause blood vessels to be inflamed.
Rituximab-pvvr injection is also used together with other medicines (eg, methotrexate) to reduce the symptoms of moderate to severe rheumatoid arthritis in patients who have been previously treated with other medicines (eg, tumor necrosis factor [TNF] antagonist) but did not work well.
Rituximab-pvvr is to be given only by or under the direct supervision of your doctor.
Before using rituximab-pvvr
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For rituximab-pvvr, the following should be considered:
Allergies
Tell your doct..
