RE DCP Drops

Generic name:dextromethorphan hydrobromide, chlorpheniramine maleate, phenylephrine hydrochloride
Dosage form: oral drops
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

DESCRIPTION:

RE DCP Drops
Antitussive – Antihistamine – Nasal Decongestant
Rx Only

Each dropperful (1 mL) contains:
Dextromethorphan HBr: 2.75 mg
Chlorpheniramine Maleate: 0.75 mg
Phenylephrine HCl: 1.75 mg

Inactive Ingredients: Cherry Flavor, Citric Acid, Glycerin, Propylene Glycol, Purified Water (Aqua), Red 40 (Cl 16035), Sodium Citrate, Sodium Saccharin, Sorbitol.

CLINICAL PHARMACOLOGY:

Antitussive, Antihistaminic, Nasal decongestant actions.

Dextromethorphan HBr:
Dextromethorphan HBr is a nonopoid antitussive agent. It suppresses the cough reflex by a direct action on the cough center in the medulla of the brain. Dextromethorphan HBr has no significant analgesic or sedative properties. It does not depress the respiration or predispose an individual to addiction with usual doses. In therapeutic dosage, Dextromethorphan HBr does not hihibit ciliary activity. The onset of action is typically within 30 minutes and the duration of actions can be up to 6 hours. Dextromethorphan is rapidly and extensively metabolized by the liver. It is primarily excreted in the kidneys as unchanged Dextromethorphan and demthylated metabolites including dextrophan, an active metabolite.

Phenylephrine Hydrochloride:
Phenylephrine HCl, a nasal decongestant, is a potent postsynaptic alpha-receptor agonist with little effect on the beta receptors of the heart and no effect on the beta-adrenegic receptors of the bronchi or peripheral blood vessels. Therapeutic doses of Phenylephrine HCl may cause vasoconstriction. It increases resistance and, to a lesser extent, decreases capacitance of blood vessels. Total peripheral resistance is increased, resulting in increased systolic and diastolic blood pressure. Pulmonary arterial pressure is usually increased, and renal blood flow is usually dec