Rea Lo 40
Generic name:urea
Dosage form: cream, lotion
Drug class:Topical emollients
Medically reviewed by Drugs.com. Last updated on Jul 22, 2021.
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
On This Page
The Rea Lo 40 brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Rx Only
DESCRIPTION
Rea Lo 40® (Urea 40%) Cream and Lotion is a keratolytic emollient, which is a gentle, yet effective, tissue softener for skin. Each gram contains 400 mg Urea as the active ingredient and the following inactive ingredients: purified water, emulsifying wax, glycerin, isopropyl myristate, sorbitol, neopentyl glycol dicaprylate/dicaprate, tridecyl stearate, tridecyl trimellitate and dimethyl isosorbide.
Urea is a diamide of carbonic acid with the following structure:
Rea Lo 40 - Clinical Pharmacology
Urea cream and lotion gently dissolves the intracellular matrix which results in loosening of the horny layer of the skin and shedding of scaly skin at regular intervals, thereby softening hyperkeratotic areas of the skin.
PHARMACOKINETICS
The exact mechanism of action of topically applied urea is not known.
INDICATION AND USAGE
Rea Lo 40® (Urea 40%) Cream and Lotion is useful for the treatment of hyperkeratotic conditions such as dry, rough skin, xerosis, ichthyosis, skin cracks and fissures, dermatitis, eczema, psoriasis, keratoses and calluses.
Contraindications
Known hypersensitivity to any of the listed ingredients.
Warnings
For external use only. Avoid contact with eyes, lips or mucous membranes.
