Asciminib
Generic name: asciminib [ as-KIM-i-nib ]
Brand name: Scemblix
Dosage form: oral tablet (20 mg; 40 mg)
Drug class:BCR-ABL tyrosine kinase inhibitors
What is asciminib?
Asciminib is used in adults to treat a type of blood cancer called Philadelphia chromosome-positive chronic myeloid leukemia (CML).
Asciminib is usually given after other treatments have failed.
Asciminib may also be used for purposes not listed in this medication guide.
Warnings
Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
Before taking this medicine
Tell your doctor if you have ever had:
inflammation of your pancreas (pancreatitis); or
heart problems or blood clots.
You may need to have a negative pregnancy test before starting this treatment.
It may be harder for you to get pregnant while you are using asciminib.
Asciminib may harm an unborn baby. Use effective birth control while you are using this medicine, and for at least 1 week after your last dose. Tell your doctor right away if you become pregnant.
You should not breastfeed while using this medicine, and for at least 1 week after your last dose.
How should I take asciminib?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Take without food.
Swallow the tablet whole and do not crush, chew, or break it.
Your blood will need to be tested often.
You should not stop using asciminib without your doctor's advice.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
If you take asciminib once a day: Take the medicine as soon as you can, but skip the missed dose if you are more than 12 hours late for the dose. Do not use two doses at one time.
If you take asciminib twice a day: Take the medicine as soon as you can, but skip the missed dose if you are more than 6 hours late for the dose. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking asciminib?
Avoid eating for at least 2 hours before and 1 hour after taking asciminib.
Asciminib side effects
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