Ribociclib
Generic name: ribociclib [ RYE-boe-SYE-klib ]
Brand names: Kisqali, Kisqali (200 mg daily dose), Kisqali (400 mg daily dose), Kisqali (600 mg daily dose)
Dosage form: oral tablet (200 mg)
Drug class:CDK 4/6 inhibitors
What is ribociclib?
Ribociclib is used to treat hormone-related breast cancer in women. Ribociclib is used only if your cancer tests negative for a protein called human epidermal growth factor receptor 2 (HER2). HER2 protein can speed the growth of cancer cells.
Ribociclib is used when the cancer has progressed or has spread to other parts of the body after other treatments.
Ribociclib is given in combination with another cancer medicine such as letrozole (Femara) or fulvestrant (Faslodex).
Ribociclib may also be used for purposes not listed in this medication guide.
Warnings
Ribociclib can cause serious side effects on your heart, liver, or lungs. Call your doctor at once if you have chest pain, fast or pounding heartbeats, trouble breathing, cough (with or without mucus), sudden dizziness, right-sided upper stomach pain, loss of appetite, unusual bleeding or bruising, dark urine, or yellowing of your skin or eyes.
You will need frequent medical tests while taking ribociclib. Your cancer treatments may be delayed based on the results of these tests. Tell your doctor if you have signs of infection, such as fever or chills.
Before taking this medicine
You should not use ribociclib if you are allergic to it, or if you also take tamoxifen.
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using ribociclib.
Tell your doctor if you have ever had:
slow heartbeats;
heart disease or prior heart attack;
an electrolyte imbalance (such as low levels of calcium, magnesium, phosphorus, or potassium in your blood);
kidney disease; or
signs of infection (fever, chills).
Tell your doctor whether or not you have gone through menopause.
You may need to have a negative pregnancy test before starting this treatment.
Do not use ribociclib if you are pregnant. It could harm the unborn baby. Use effective
