Asparaginase Erwinia chrysanthemi
Generic name: asparaginase Erwinia chrysanthemi [ as-PAR-a-jin-ase-er-WIN-ee-a-kri-SAN-the-mee ]
Brand names: Erwinaze, Rylaze, Erwinase
Dosage forms: injectable powder for injection (10000 intl units); intramuscular solution (rywn recombinant 10 mg/0.5 mL)
Drug class:Miscellaneous antineoplastics
What is asparaginase Erwinia chrysanthemi?
Asparaginase Erwinia chrysanthemi is a cancer medicine.
Erwinaze is used to treat acute lymphoblastic leukemia in adults and children at least 1 year old.
Rylaze is used to treat lymphoblastic lymphoma in adults and children at least 1 month old who have become allergic to other forms of asparaginase such as Elspar or Oncaspar.
Asparaginase Erwinia chrysanthemi may also be used for purposes not listed in this medication guide.
Warnings
Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
Before taking this medicine
You should not use asparaginase Erwinia chrysanthemi if you have received any form of asparaginase in the past and it caused you to have:
a serious allergic reaction;
serious pancreas problems;
a life-threatening blood clot; or
serious bleeding problems.
Tell your doctor if you have ever had:
problems with your liver or pancreas;
bleeding problems;
a blood clot; or
diabetes.
May harm an unborn baby. You may need a pregnancy test to make sure you are not pregnant. Use birth control while using this medicine and for at least 3 months after your last dose. Tell your doctor if you become pregnant.
Asparaginase Erwinia chrysanthemi can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. Use barrier birth control to prevent pregnancy: condom, diaphragm, cervical cap, or contraceptive sponge.
Do not breastfeed while using this medicine, and for at least 3 months after your last dose of Erwinaze or 1 week after your last dose of Rylaze.
How should I use asparaginase Erwinia chrysanthemi?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Asparaginase Erwinia chrysanthemi is injected into a muscle or into a vein. Erwinaze is usually given e...
