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Aspirin and omeprazole
  • Treatments
  • Prevention of Cardiovascular Disease

Aspirin and omeprazole

Generic name: aspirin and omeprazole [ AS-pir-in-and-oh-MEP-ra-zole ]
Brand name: Yosprala
Dosage form: oral delayed release tablet (325 mg-40 mg; 81 mg-40 mg)
Drug class:Platelet aggregation inhibitors

Medically reviewed by Drugs.com on Jan 14, 2021. Written by Cerner Multum.

What is aspirin and omeprazole?

Aspirin and omeprazole is a combination medicine used to help lower the risk of heart problems, strokes, or death in people who have had heart problems caused by blood clots.

Aspirin and omeprazole is also used in people who have had surgery to improve blood flow to the heart and also have another condition that is already being treated with aspirin.

Omeprazole helps reduce the risk of stomach ulcers that may be caused by aspirin, especially in people who are 55 or older, or those who have had stomach ulcers in the past.

Aspirin and omeprazole may also be used for purposes not listed in this medication guide.

Warnings

Aspirin can make you bleed more easily. Call your doctor if you have any unusual bleeding or bruising, or if you cough up blood or have bloody or tarry stools.

Omeprazole can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine.

Diarrhea may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it.

Omeprazole may cause new or worsening symptoms of lupus. Tell your doctor if you have joint pain and a skin rash on your cheeks or arms that worsens in sunlight.

You may be more likely to have a broken bone while taking aspirin and omeprazole long term or more than once per day.

Before taking this medicine

You should not use this medicine if you are allergic to aspirin or omeprazole, or if: