Generic name: cyanocobalamin
Dosage form: injection, USP
Drug class:Vitamins
Medically reviewed by Drugs.com. Last updated on Sep 21, 2021.
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Rubramin PC Description
Rubramin PC (Cyanocobalamin Injection) contains cyanocobalamin (vitamin B12) in a clear, red, sterile, nonpyrogenic, aqueous solution in a potency of 1000 mcg/mL (cobalt: 40 mcg/mL) for intramuscular use. Each mL of solution also contains 10 mg benzyl alcohol as a preservative and sodium chloride for isotonicity; pH has been adjusted between 4.5 and 7.0 with sodium hydroxide or hydrochloric acid.
Cyanocobalamin is very hygroscopic in the anhydrous form, and sparingly soluble in water (1:80). The vitamin B12 coenzymes are very unstable in light.
Cyanocobalamin may be chemically designated as 5,6-dimethyl-benzimidazolyl cyanocobamide. The structural formula is represented below:
Rubramin PC - Clinical Pharmacology
Vitamin B12 is essential to growth, cell reproduction, hematopoiesis, and nucleoprotein and myelin synthesis.
Cyanocobalamin is quantitatively and rapidly absorbed from intramuscular sites of injection; the plasma level of the compound reaches its peak within one hour after intramuscula...
