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Ruconest
  • Treatments
  • Hereditary Angioedema

Ruconest

Generic name:c1 esterase inhibitor recombinant injection (conestat alfa)
Drug class:Hereditary angioedema agents

Medically reviewed by Philip Thornton, DipPharm. Last updated on Mar 30, 2021.

What is Ruconest?

Ruconest is a manmade form of the c1 esterase inhibitor protein that occurs naturally in the bloodstream and helps control swelling in the body. People with a condition called Hereditary Angioedema do not have enough of this protein. Hereditary Angioedema can cause attacks of swelling and symptoms such as stomach problems or trouble breathing.

Ruconest is an injectable medicine used to treat acute angioedema attacks in in adult and adolescent patients with Hereditary Angioedema.

Ruconest is for use in adults and children who are at least 13 years old.

Warnings

You should not use Ruconest if you are allergic to rabbits or rabbit products (meat, fur, pelt).

You should not use Ruconest if you have experienced life-threatening immediate hypersensitivity reactions, including anaphylaxis, to this medicine or to any other C1 esterase inhibitor product.

Before taking this medicine

You should not use Ruconest if you are allergic to c1 esterase inhibitor, or:

  • if you are allergic to rabbits or rabbit products (meat, fur, pelt); or

  • if you have ever had a life-threatening allergic reaction to Ruconest or to another C1 esterase inhibitor (such as Berinert or Cinryze).

To make sure Ruconest is safe for you, tell your doctor if you have:

This medicine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether c1 esterase inhibitor passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Ruconest is not approved for use by anyone younger than 13 years old.

How is Ruconest given?

Use Ruconest exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Ruconest is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

Ruconest is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine. Ask your pharmacist what type of diluent can safely be mixed with this medicine powder.

Wash your hands before mixing the medicine or preparing your injection.

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