Salitop Lotion
Generic name:salicylic acid
Dosage form: lotion
Drug classes:Topical acne agents, Topical keratolytics
Medically reviewed by Drugs.com. Last updated on Dec 22, 2021.
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
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FOR DERMATOLOGICAL USE ONLY. NOT FOR OPHTHALMIC, ORAL OR INTRAVAGINAL USE.
The Salitop brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Salitop Lotion Description
Salitop™ Cream contains 6% w/w Salicylic Acid USP finely dispersed in an emulsion consisting of Ammonium Lactate, Behentrimonium Chloride, Cetyl Alcohol, Dimethicone 360, Disodium EDTA, Glycerin, Glyceryl Stearate SE, Methylparaben, Mineral Oil, PEG-100 Stearate, Phenoxyethanol, Propylparaben, Purified Water and Trolamine.
Salitop™ Lotion contains 6% w/w Salicylic Acid USP finely dispersed in an emulsion consisting of Ammonium Lactate, Behentrimonium Chloride, Cetyl Alcohol, Dimethicone 360, Disodium EDTA, Glycerin, Glyceryl Stearate SE, Methylparaben, Mineral Oil, PEG-100 Stearate, Propylparaben, Purified Water, Trolamine.
Salicylic acid is the 2-hydroxy derivative of benzoic acid having the following structure:
This formulation is designed to provide sustained release of the active ingredient into the skin.
Salitop Lotion - Clinical Pharmacology
Salicylic acid has been shown to produce desquamation of the horny layer of skin while not effecting qualitative or quantitative changes in the structure of the viable epidermis. The mechanism of action has been attributed to a dissolution of intercellular cement substance. In a study of the percutaneous absorption of salicylic acid in a 6% salicylic acid gel in fo...
