Class: Selective beta-2-Adrenergic Agonists
VA Class: RE102
Chemical Name: ±-4-Hydroxy-α1 -[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol compd. with 1-hydroxy-2-naphthalenecarboxylic acid (1:1)
Molecular Formula: C25H37NO4•C11 H8O3
CAS Number: 94749-08-3
Warning
Monotherapy with long-acting β2-adrenergic agonists (e.g., salmeterol) increases the risk of asthma-related death and may increase the risk of asthma-related hospitalization in children and adolescents. (See Asthma-related Death and Life-threatening Events under Cautions.)
Use of salmeterol for treatment of asthma without concomitant use of long-term asthma controller therapy (e.g., inhaled corticosteroids) is contraindicated. (See Contraindications under Cautions.)
Use salmeterol only as additional therapy in patients with asthma currently receiving long-term asthma controller therapy (e.g., inhaled corticosteroids) but whose disease is inadequately controlled with such therapy. (See Bronchospasm in Asthma under Uses.)
Use salmeterol in fixed combination with fluticasone only in patients with asthma not responding adequately to long-term asthma controller therapy (e.g., inhaled corticosteroids) or whose disease severity warrants initiation of treatment with both an inhaled corticosteroid and a long-acting β2-adrenergic agonist. (See Bronchospasm in Asthma under Uses.)
Introduction
Bronchodilator; a relatively selective, long-acting β2-adrenergic agonist.
Uses for Salmeterol
Bronchospasm in Asthma
Salmeterol is used only concomitantly with long-term asthma controller therapy (e.g., inhaled corticosteroids) for treatment of asthma and prevention of bronchospasm in patients with reversible obstructive airway disease, including symptoms of nocturnal asthma.
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