Sarilumab
Generic name: sarilumab [ sar-IL-ue-mab ]
Brand names: Kevzara, Kevzara Pre-filled Pen
Dosage form: subcutaneous solution (150 mg/1.14 mL; 200 mg/1.14 mL)
Drug classes:Antirheumatics, Interleukin inhibitors
What is sarilumab?
Sarilumab is used to treat moderate to severe rheumatoid arthritis in adults. Sarilumab is sometimes given together with other arthritis medicines.
Sarilumab is usually given after other treatments have failed.
Sarilumab may also be used for purposes not listed in this medication guide.
Warnings
Sarilumab affects your immune system. You may get infections more easily, even serious or fatal infections. Tell your doctor if you have a fever, chills, tiredness, cough, diarrhea, stomach pain, weight loss, skin sores, or painful urination.
Sarilumab may cause you to have a tear in your stomach or intestines. This is more likely if you have diverticulitis or a stomach ulcer, or if you also take steroids, methotrexate, or an NSAID (nonsteroidal anti-inflammatory drug). Call your doctor right away if you have a fever and ongoing stomach pain.
Before taking this medicine
You should not use sarilumab if you are allergic to it.
Tell your doctor if you have ever had tuberculosis or if anyone in your household has tuberculosis. Also tell your doctor if you have recently traveled. Tuberculosis and some fungal infections are more common in certain parts of the world, and you may have been exposed during travel.
Tell your doctor if you have ever had:
an active or chronic infection;
diabetes;
HIV or AIDS;
a weak immune system;
hepatitis or other liver problems;
stomach pain, diverticulitis, or stomach or intestinal ulcers;
cancer; or
if you have received or are scheduled to receive any vaccines.
Using sarilumab may increase your risk of developing certain types of cancers. Ask your doctor about this risk.
It is not known whether sarilumab will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of sarilumab on the baby.
You should not breast-feed while using sarilumab.
How should I take sarilumab?
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