Satralizumab
Generic name: satralizumab [ SAT-ra-LIZ-ue-mab ]
Brand name: Enspryng
Dosage form: subcutaneous solution (120 mg/mL)
Drug class:Interleukin inhibitors
What is satralizumab?
Satralizumab is used to treat adults with neuromyelitis optica spectrum disorder (NMOSD). NMOSD is a rare, chronic autoimmune disease that causes inflammation in the central nervous system. This can lead to damage of the optic nerves, spinal cord, and/or brain.
Satralizumab is used only if your body produces antibodies to a protein called aquaporin-4 (AQP4). Your doctor will test you for this antibody.
Satralizumab may also be used for purposes not listed in this medication guide.
Warnings
Satralizumab affects your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have signs of infection (fever, chills, cough, tiredness, muscle pain, diarrhea, stomach cramps, increased urination, burning when you urinate, skin sores or redness, swelling or tenderness).
Before taking this medicine
You should not use satralizumab if you are allergic to it, or if you have an active infection such as:
hepatitis B; or
Tell your doctor if you have ever had tuberculosis, if anyone in your household has tuberculosis, or if you have recently traveled to an area where tuberculosis is common.
Tell your doctor if you have ever had:
an active or chronic infection;
liver problems, hepatitis B (or if you are a carrier of hepatitis B); or
if you have recently received or are scheduled to receive a vaccine.
Make sure you are current on all vaccines before you begin treatment with satralizumab.
You should not receive a "live" vaccine for at least 4 weeks before using satralizumab. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.
You should not receive a "non-live" (sometimes called inactivated) vaccine for at least 2 weeks before using satralizumab. Non-live vaccines include the flu (influenza) shot and injected vaccines for hepatitis A, polio, or rabies.
Tell your doctor if you are pregnant or breastfeeding.
If you use satralizumab while you are pregnant, make sure any doctor caring for your new baby knows that you used satralizumab during pregnancy. Being exposed to satralizumab in the womb could affect your baby's vaccination schedule.
How should I use satralizumab?
Your doctor may perfo...
