Savaysa

Generic name:edoxaban [ e-DOX-a-ban ]
Drug class:Factor Xa inhibitors

Medically reviewed by Sophia Entringer, PharmD. Last updated on Nov 19, 2021.

What is Savaysa?

Savaysa blocks the activity of certain clotting substances in the blood.

Savaysa is used to lower the risk of stroke caused by a blood clot in people with a heart rhythm disorder called atrial fibrillation. This medicine is used when the atrial fibrillation is not caused by a heart valve problem.

Savaysa is also used to treat a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism). Savaysa should be used after 5 to 10 days of using an injectable blood thinner.

Warnings

Savaysa can cause you to bleed more easily. Call your doctor at once if you have signs of bleeding such as: bleeding gums, nosebleeds, heavy menstrual periods or abnormal vaginal bleeding, blood in your urine, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Many other drugs can increase your risk of bleeding when used with Savaysa. Tell your doctor about all medicines you have recently used.

Savaysa can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). Tell any doctor who treats you that you are taking this medicine.

Do not stop taking Savaysa without first talking to your doctor. Stopping suddenly can increase your risk of blood clot or stroke.

Before taking this medicine

You should not use Savaysa if you are allergic to edoxaban, or if you have active or uncontrolled bleeding.

Savaysa can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). This type of blood clot could cause long-term paralysis, and may be more likely to occur if:

• you have a genetic spinal defect;

• you have a spinal catheter in place;

• you have a history of spinal surgery or repeated spinal taps;

• you have recently had a spinal tap or epidural anesthesia;

• you are taking an NSAID - Advil, Aleve, Motrin, and others; or

• you are using other medicines to treat or prevent blood clots.

Savaysa may cause you to bleed more easily, especially if you have:

• a bleeding disorder that is inherited or caused by disease;

• hemorrhagic stroke;

• uncontrolled high blood pressure;

• stomach or intestinal bleedi...