Saxagliptin and dapagliflozin (Oral)

Medically reviewed by Drugs.com. Last updated on Nov 30, 2021.

Commonly used brand name(s)

In the U.S.

• Qtern

Available Dosage Forms:

• Tablet

Therapeutic Class: Hypoglycemic

Pharmacologic Class: Dipeptidyl Peptidase IV Inhibitor

Uses for saxagliptin and dapagliflozin

Saxagliptin and dapagliflozin combination is used together with proper diet and exercise to treat type 2 diabetes. Saxagliptin helps to control blood sugar levels by making the pancreas gland release more insulin. It also signals the liver to stop producing sugar when there is too much sugar in the blood. Dapagliflozin works in the kidneys to prevent absorption of glucose (blood sugar). This helps lower the blood sugar level. Saxagliptin and dapagliflozin does not help patients who have insulin-dependent or type 1 diabetes. Type 1 diabetic patients must use insulin injections.

Saxagliptin and dapagliflozin is available only with your doctor's prescription.

Before using saxagliptin and dapagliflozin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For saxagliptin and dapagliflozin, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to saxagliptin and dapagliflozin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of saxagliptin and dapagliflozin combination in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of saxagliptin and dapagliflozin combination in the elderly. However, elderly patients are more likely to have kidney problems, which may require caution and an adjustment in the dose for patients receiving saxagliptin and dapagliflozin.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking saxagliptin and dapagliflozin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using saxagliptin and dapagliflozin with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Abametapir
• Balofl...