Scemblix

Generic name:asciminib
Dosage form: tablets
Drug class:BCR-ABL tyrosine kinase inhibitors

Medically reviewed by Judith Stewart, BPharm. Last updated on Oct 30, 2021.

What is Scemblix?

Scemblix is a prescription medicine used to treat adults with:

• Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase (CP), previously treated with 2 or more tyrosine kinase inhibitor (TKI) medicines.
• Ph+ CML in CP with the T315I mutation.

It is not known if this medicine is safe and effective in children.

Before taking Scemblix

Before you start treatment, tell your healthcare provider about all of your medical conditions, including if you:

• have a history of inflammation of your pancreas (pancreatitis)
• have a history of heart problems or blood clots in your arteries and veins (types of blood vessels)
• are pregnant or plan to become pregnant. Scemblix can harm your unborn baby.
  • Your healthcare provider will do a pregnancy test before you start treatment.
  • Females who are able to become pregnant should use effective birth control during treatment and for 1 week after your last dose. Talk to your healthcare provider about birth control methods that may be right for you.
  • Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment.
• are breastfeeding or plan to breastfeed. It is not known if Scemblix passes into your breast milk. Do not breastfeed during treatment and for 1 week after your last dose.

What other drugs will affect Scemblix?

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Scemblix and other medicines may affect each other causing side effects.

Especially tell your doctor if you take:

• antibiotics - clarithromycin
• antifungal medici..