Sebelipase alfa (Intravenous)
Medically reviewed by Drugs.com. Last updated on Nov 5, 2021.
Commonly used brand name(s)
In the U.S.
- Kanuma
Available Dosage Forms:
- Solution
Therapeutic Class: Enzyme Replacement
Pharmacologic Class: Enzyme
Uses for sebelipase alfa
Sebelipase alfa injection is used to treat patients with Lysosomal acid lipase (LAL) deficiency.
Sebelipase alfa is to be given by or under the direct supervision of your doctor.
Before using sebelipase alfa
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For sebelipase alfa, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to sebelipase alfa or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of sebelipase alfa injection in children 1 month of age and older.
Geriatric
Although appropriate studies on the relationship of age to the effects of sebelipase alfa injection have not been performed in the geriatric population, no geriatric-specific problems have been documented to date.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of sebelipase alfa. Make sure you tell your doctor if you have any other medical problems, especially:
- Allergy to eggs or egg products—May increase risk for allergic reactions to occur again.
Proper use of sebelipase alfa
A nurse or other trained health professional will give you sebelipase alfa in a hospital. Sebelipase alfa is given through a needle placed in one of your veins. It is usually given for at least 2 hours once a week, or once every other week.